Long Noncoding RNA in Hematopoiesis and Immunity
نویسندگان
چکیده
منابع مشابه
Long noncoding RNAs in hematopoiesis
Mammalian development is under tight control to ensure precise gene expression. Recent studies reveal a new layer of regulation of gene expression mediated by long noncoding RNAs. These transcripts are longer than 200nt that do not have functional protein coding capacity. Interestingly, many of these long noncoding RNAs are expressed with high specificity in different types of cells, tissues, a...
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Genome and transcriptome sequencing have revealed a rich assortment of noncoding RNAs in eukaryote cells, including long noncoding RNAs (lncRNAs), which regulate gene expression independent of protein coding potential. LncRNAs modulate protein coding gene expression in many cell types by regulating multiple processes, including epigenetic control of transcription, mRNA stability, and protein lo...
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Once seen as potential sequencing artifacts, long-noncoding RNAs (lncRNAs; >200 nucleotides) have gained recognition as important regulatory factors. lncRNAs are transcribed from a variety of genomic locations (introns, intergenic spaces, and coding regions) from the sense or antisense strand (reviewed in Chekanova, 2015). Moreover, lncRNAs function in cis or in trans and affect gene regulation...
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Introduction: Breast cancer is the second most common cause of cancer-related death among females, which requires an exploration for markers to propose a more specific categorization of this cancer. Long noncoding RNAs (lncRNAs), the main subset of noncoding transcripts, are involved in tumorigenic processes. In this study, we investigated the expression of the fer-1–like family member 4 (FER...
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ژورنال
عنوان ژورنال: Immunity
سال: 2015
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2015.05.004